发明名称 |
Peripheral Opioid Agonists and Peripheral Opioid Antagonists |
摘要 |
The present disclosure provides compositions, and their methods of use, where the compositions comprise a ketone-modified opioid drug, wherein the drug comprises a ketone-modified opioid and a substituent on the opioid that mediates retention of the drug in the peripheral nervous system as opposed to the central nervous system following ingestion by a subject. |
申请公布号 |
US2013079364(A1) |
申请公布日期 |
2013.03.28 |
申请号 |
US201113634532 |
申请日期 |
2011.04.08 |
申请人 |
JENKINS THOMAS E.;HUSFELD CRAIG O.;SIGNATURE THERAPEUTICS, INC. |
发明人 |
JENKINS THOMAS E.;HUSFELD CRAIG O. |
分类号 |
A61K31/439;C07D489/02 |
主分类号 |
A61K31/439 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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