PNEUMOCOCCAL GLPO IMMUNOGEN

摘要

An immunogenic composition, that may be a vaccine comprising GlpO or a fragment thereof suitable for use in the treatment or prevention of a streptococcal infection, in particular meningitis. The GlpO or fragment thereof is preferably enzymatically inactive. In a preferred form immunogenic comprises additionally a further immunogen known to be protective against steptococcal infection which further immunogen is preferably a protein. One particularly illustrated such further protein is a non-toxic pneumolysin.