METALLOINSERTOR COMPLEXES TARGETED TO DNA MISMATCHES
摘要
A composition including a Rh or Ru metalloinsertor complex specifically targets mismatch repair (MMR)-deficient cells. Selective cytotoxicity is induced in MMR-deficient cells upon uptake of the inventive metalloinsertor complexes.
申请公布号
WO2012155004(A3)
申请公布日期
2013.03.28
申请号
WO2012US37403
申请日期
2012.05.10
申请人
CALIFORNIA INSITUTE OF TECHNOLOGY;BARTON, JACQUELINE, K.;KOMOR, ALEXIS;SCHNEIDER, CURTIS, J.;WEIDMANN, ALYSON;ERNST, RUSSELL
发明人
BARTON, JACQUELINE, K.;KOMOR, ALEXIS;SCHNEIDER, CURTIS, J.;WEIDMANN, ALYSON;ERNST, RUSSELL
