MU-OPIOID RECEPTOR BINDING COMPOUNDS

摘要

A pharmaceutical composition, comprising (i) a mu opioid receptor modulating compound selected from the group consisting of Group I compounds, Matching Compounds, and their pharmaceutically acceptable derivatives, (ii) a pharmaceutically acceptable carrier, and (iii) optionally, another therapeutic agent. Also described are therapeutic methods of administering mu opioid receptor modulating compounds, and cocktail formulations with other mu opioid receptor compounds, e.g., morphine, (+)-morphine, methadone, (+)-methadone, 3-methoxynaltrexone, etorphine, or naltrexone.