发明名称 |
PHENYLIMIDE-CONTAINING BENZOTHIAZOLE DERIVATIVE OR ITS SALT AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME |
摘要 |
The present invention provides a phenylimide-containing benzothiazole derivative or its pharmaceutically acceptable salt, a process for the preparation thereof, and a pharmaceutical composition comprising the same. The phenylimide-containing benzothiazole derivative or its pharmaceutically acceptable salt can selectively inhibit the protein-protein interaction between KRS and a laminin receptor (LR), thereby inhibiting migration of cancer cells. Therefore, the phenylimide-containing benzothiazole derivative or its pharmaceutically acceptable salt may be usefully applied for preventing or treating the diseases associated with cancer cell metastasis. |
申请公布号 |
CA2849702(A1) |
申请公布日期 |
2013.03.28 |
申请号 |
CA20122849702 |
申请日期 |
2012.09.21 |
申请人 |
YUHAN CORPORATION |
发明人 |
HUR, YOUN;KIM, DONG-HYUN;KIM, EUN-KYUNG;PARK, JIN-HWI;JOO, JAE-EUN;KANG, HO-WOONG;OH, SE-WOONG;KIM, DONG-KYUN;AHN, KYOUNG-KYU |
分类号 |
C07D277/82;A61K31/428;A61P35/00;C07D513/04 |
主分类号 |
C07D277/82 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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