METHOD FOR INDIVIDUAL SELECTION OF DRUG PREPARATIONS IN THERAPY OF ARTERIAL HYPERTENSION

摘要

FIELD: medicine.SUBSTANCE: invention refers to medicine, particularly clinical pharmacology and cardiology, and may be used for achieving target arterial pressure in the patients suffering degree 1-2 arterial hypertension (AH). A start antihypertensive preparation is individually selected by taking into account systolic arterial blood pressure (SABP) variations in passive orthostatic test. The measurements are taken in an initial horizontal position on the first, fifth, tenth and fifteenth minutes of the test. A response index (RI) is calculated by formula:If the RI is less than zero, a monotherapy with an angiotensin converting enzyme inhibitor is required. If the RI is equal to zero or more, a combined therapy with the angiotensin converting enzyme inhibitor Zofenopril and the beta-adrenoreceptor blocking agent Nebivolol is required.EFFECT: method provides a differentiated approach to selection of the start therapy in this group of patients for achieving target pressure.2 ex