The invention provides human engineered antibodies, antigen-binding fragments thereof, that bind to, and inhibit the activity of, human DKK-1, and which are effective in treating diseases in which pathogenesis is mediated by DKK-1.
申请公布号
ZA201107256(B)
申请公布日期
2013.03.27
申请号
ZA20110007256
申请日期
2011.10.04
申请人
ELI LILLY AND COMPANY
发明人
CHEDID MARCIO;GALVIN RACHELLE JEANETTE;DARLING RYAN JAMES;SWANSON BARBARA ANNE