发明名称 PYRAZOLOPYRIMIDINE JAK INHIBITOR COMPOUNDS AND METHODS
摘要 A compound of Formula I, enantiomers, diasteriomers, tautomers or pharmaceutically acceptable salts thereof, wherein R1, R2 and R3 are defined herein, are useful as inhibitors of one or more Janus kinases. A pharmaceutical composition that includes a compound of Formula I and a pharmaceutically acceptable carrier, adjuvant or vehicle, and methods of treating or lessening the severity of a disease or condition responsive to the inhibition of a Janus kinase activity in a patient are disclosed.
申请公布号 ZA201200490(B) 申请公布日期 2013.03.27
申请号 ZA20120000490 申请日期 2012.01.20
申请人 GENENTECH INC 发明人 GIBBONS PAUL A;HANAN EMILY;LIU WENDY;LYSSIKATOS JOSEPH P;MAGNUSON STEVEN R;MENDONCA ROHAN;PASTOR RICHARD D;RAWSON THOMAS E;SIU MICHAEL;ZAK MARK E;ZHOU AIHE;ZHU BING-YAN
分类号 C07D;A61K;A61P 主分类号 C07D
代理机构 代理人
主权项
地址