| 摘要 |
FIELD: medicine.SUBSTANCE: invention refers to medical equipment, namely to ultrasonic devices for transdermal drug delivery. A plaster contains an adhesive layer as a base layer, a directly adjoining drug layer, an ultrasonic transducer, an exciting unit and a coating layer. The drug layer, the ultrasound transducer and the exciting unit are arranged in the form of successive bottom-up layers, while the coating layer covers said three layers. A method for preparing the plaster involves the stages whereat one surface of the adhesive layer is coated with an agent with an opposite surface of the adhesive layer contains two surface areas - a first area and a second area. The adhesive layer is the lowest layer of the plaster and made of a flexible material possessing good permeability. That is followed by fixing the drug layer, the ultrasonic transducer and the exciting unit in the first area; thereafter the second area is coated with the adhesive agent and combined with the coating layer; the drug is sprayed over an adsorbent material, or the adsorbent material is impregnated with the drug to form the drug layer. The drug layer is fixed on the first surface with the surface of the ultrasonic transducer emitting ultrasonic waves being directly attached to the drug layer. A power on/off film is used to find a power source in an off position with one end of the film being open from an external side of the plaster to remove the film when in use in order to activate the power source; the drug layer, the ultrasonic transducer and the exciting unit are coated with the coating layer and fixed on the first layer by means of a part of the coating layer; another part is combined with the second area of the adhesive layer to form a freely flexing edge so that to make the plaster placed on an uneven skin surface of human body.EFFECT: use of the invention enables higher working efficiency ensured by generating more uniform and regular ultrasonic field, as well as simplifying plaster technology.12 cl, 6 dwg. |
