| 摘要 |
<p>Substituted spirocyclic amines of structural formula (I) are selective antagonists of the somatostatin subtype receptor 5 (SSTR5) and are useful for the treatment, control or prevention of disorders responsive to antagonism of SSTR5, such as Type 2 diabetes, insulin resistance, lipid disorders, obesity, atherosclerosis, Metabolic Syndrome, depression, and anxiety.</p> |
| 申请人 |
MERCK SHARP & DOHME CORP. |
发明人 |
DUFFY, JOSEPH, L.;BAO, JIANMING;ONDEYKA, DEBRA, L.;TYAGARAJAN, SRIRAM;SHAO, PATRICK;YE, FENG;KATIPALLY, REVATHI;FINKE, PAUL, E.;ZANG, YI;PLOTKIN, MICHAEL, A.;ROMERO, F. ANTHONY;MONINGKA, REMOND;HUSSAIN, ZAHID |
