发明名称 |
High affinity binding site of HGFR and methods for identification of antagonists thereof |
摘要 |
Use of a polynucleotide encoding or a polypeptide comprising at least the extracellular IPT-3 and IPT-4 domains of hepatocyte growth factor receptor for the screening and/or development of pharmacologically active agents useful in the treatment of cancer, preferably a cancer with dysregulation of hepatocyte growth factor receptor.
|
申请公布号 |
US8404453(B2) |
申请公布日期 |
2013.03.26 |
申请号 |
US20090465307 |
申请日期 |
2009.05.13 |
申请人 |
BASILICO CRISTINA;MICHIELI PAOLO;CARMINATI PAOLO;COMOGLIO PAOLO MARIA;METHERESIS TRANSLATIONAL RESEARCH SA |
发明人 |
BASILICO CRISTINA;MICHIELI PAOLO;CARMINATI PAOLO;COMOGLIO PAOLO MARIA |
分类号 |
C12Q1/48;C07K14/71;G01N33/48;G01N33/483;G01N33/50 |
主分类号 |
C12Q1/48 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|