发明名称 |
Pyrrolidine derivatives as NK2 receptor antagonists |
摘要 |
The present invention relates to compounds of formula I wherein R1, R2, R3, Ar and n are as defined herein and pharmaceutically active salts, racemic mixtures, enantiomers, optical isomers or tautomeric forms thereof. The compounds can be used for the treatment of depression, anxiety or schizophrenia. |
申请公布号 |
US8404679(B2) |
申请公布日期 |
2013.03.26 |
申请号 |
US201213452981 |
申请日期 |
2012.04.23 |
申请人 |
BISSANTZ CATERINA;JABLONSKI PHILIPPE;KNUST HENNER;KOBLET ANDREAS;LIMBERG ANJA;NETTEKOVEN MATTHIAS;RATNI HASANE;RIEMER CLAUS;HOFFMANN-LA ROCHE INC. |
发明人 |
BISSANTZ CATERINA;JABLONSKI PHILIPPE;KNUST HENNER;KOBLET ANDREAS;LIMBERG ANJA;NETTEKOVEN MATTHIAS;RATNI HASANE;RIEMER CLAUS |
分类号 |
A61K31/496;A61K31/454;A61K31/498;A61K31/501;A61K31/5377;A61K31/541;C07D207/14;C07D401/06;C07D401/14;C07D403/06;C07D403/12;C07D405/06;C07D405/12;C07D405/14;C07D417/06 |
主分类号 |
A61K31/496 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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