发明名称 A combined irradiation method with polyglutamic acid for preventing the decrease in the physical and physiological properties of skin or tendon tissues and skin or tendon substitutes by sterilization
摘要 PURPOSE: A radiation sterilizing method of skin regeneration organization or ligament renewal tissue is provided to prevent transformation or degradation of physical properties of skin or ligament transplant material. CONSTITUTION: A radiation sterilizing method of skin regeneration organization or ligament renewal tissue comprises the following steps: adding polyglutamic acid to a transplant material; and suppressing transformation of the physical properties of skin or ligament transplant material by irradiating radiation. The radiation irradiation uses one of gamma-ray, electron beam and X-ray at the absorption dose of 1-100kGy. The skin transplant material is allogenic skin transplant material or heterodermic skin transplant material. The ligament transplant material is allogenic ligament transplant material or different kind ligament transplant material. [Reference numerals] (AA) Non-irradiation; (BB) 30kGy irradiation; (CC) Non-processed area; (DD) Epidermis; (EE) Dermis; (FF) Striatum papillae of dermis; (GG) Straiatum reticulum of dermis; (HH) Polyglutamic acid added area
申请公布号 KR101246721(B1) 申请公布日期 2013.03.26
申请号 KR20110056889 申请日期 2011.06.13
申请人 发明人
分类号 A61K31/198;A61N5/10 主分类号 A61K31/198
代理机构 代理人
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