| 发明名称 |
Compositions and methods of using chondroitinase ABCI mutants |
| 摘要 |
The present invention relates to protein and nucleic acid mutants of chondroitinase ABCI. Such chondroitinase ABCI mutant enzymes exhibit altered chondroitin lyase activity or increased resistance to inactivation from stressors including UV light or heat. Methods of using chondroitinase ABCI mutant enzymes are also provided.
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| 申请公布号 |
US8404232(B2) |
申请公布日期 |
2013.03.26 |
| 申请号 |
US20100781762 |
申请日期 |
2010.05.17 |
| 申请人 |
CAGGIANO ANTHONY O.;VECCHIONE ANDREA;IACI JENNIFER;ACORDA THERAPEUTICS, INC. |
发明人 |
CAGGIANO ANTHONY O.;VECCHIONE ANDREA;IACI JENNIFER |
| 分类号 |
A61K38/00;A61K38/46;A61M37/00;C07H21/04;C07K1/00;C12N9/88 |
主分类号 |
A61K38/00 |
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