发明名称 8-HYDROXY-QUINOLINE DERIVATIVES
摘要 The invention relates to compounds of the general formula (I) and their pharmaceutically acceptable salts (in which formula R1 represents a hydrogen atom, lower alkyl group, lower alkenyl group, lower cycloalkyl group, aryl group, aralkyl group or heterocyclic group, wherein, the above groups are optionally substituted in ortho, meta and/or para position with 1, 2, 3 or 4 electron withdrawing groups or electron donating groups; R2 represents a hydrogen atom, lower alkyl group, aryl group, aralkyl group or heterocyclic group wherein the above groups are optionally substituted with one or more halogen atoms; R3 represents a lower alkyl group, aryl group, aralkyl group or heterocyclic group wherein the above groups are optionally substituted in ortho, meta or para position with 1, 2, 3 or 4 electron withdrawing groups or electron donating groups; R4 represents a hydrogen atom, lower alkyl group or any acidic functional group; n is 1 or 2). The compounds according to the invention can be used in the medicine mainly for the treatment of diseases associated with neurological and/or oxidative stress.
申请公布号 KR20130029772(A) 申请公布日期 2013.03.25
申请号 KR20127030702 申请日期 2011.05.06
申请人 UBICHEM KUTATO KORLATOLT FELELOSSEGU TARSASAG;AVIDIN KUTATO, FEJLESZTO ES KERESKEDELMI KORLATOLT FELELOSSEGU TARSASAG 发明人 PUSKAS LASZLO;SZABO CSABA;KANIZSAI IVAN;GYURIS MARIO;MADACSI RAMONA;OZSVARI BELA;FEHER LILIANA;TAMAS GABOR
分类号 C07D401/12;A61K31/4709;A61P9/10;C07D215/26 主分类号 C07D401/12
代理机构 代理人
主权项
地址