CRYSTALLINE MALEATE SALTS OF QUINAZOLINE DERIVATIVES (FORM A AND FORM B), PHARMACEUTICAL COMPOSITIONS COMPRISING THEM, PROCESSES FOR THEIR PREPARATION AND USE THEREOF IN THE MANUFACTURE OF MEDICAMENTS FOR THE PRODUCTION OF AN ANTIANGIOGENIC AND /OR VASCULAR PERMEABILITY REDUCING EFFECT IN A WARM-BLOODED ANIMAL

摘要

The present invention relates to AZD2171 maleate salt, to particular crystalline forms of AZD2171 maleate salt, to processes for their preparation, to pharmaceutical compositions containing them as active ingredient, to their use in the manufacture of medicaments for use in the production of antiangiogenic and/or vascular permeability reducing effects in warm-blooded animals such as humans, and to their use in methods for the treatment of disease states associated with angiogenesis and/or increased vascular permeability.