| 发明名称 |
ISOLATED TRUNCATED MAMMALIAN URICASE COMPRISING AN AMINO ACID SUBSTITUTION AT POSITION 46, THE SAID TRUNCATION AND AMINO ACID SUBSTITUTION BEING RELATIVE TO A NATURALLY OCCURRING PIG URICASE |
| 摘要 |
<p>Genetically modified proteins with uricolytic activity are described. Proteins comprising truncated urate oxidases and methods for producing them, including PEGylated proteins comprising truncated urate oxidase are described.</p> |
| 申请公布号 |
IL186510(A) |
申请公布日期 |
2013.03.24 |
| 申请号 |
IL20070186510 |
申请日期 |
2007.10.09 |
| 申请人 |
SAVIENT PHARMACEUTICALS, INC. |
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