发明名称 METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE BY MEANS OF COUPLING METHOD USING A PALLADIUM COMPOUND.
摘要 <p>The present invention provides a method for producing a xanthine oxidase inhibitor, which is a therapeutic agent for hyperuricemia, or intermediates of the same, said method being efficient and using a short-procedure. The present invention is a novel coupling method for obtaining a compound represented by formula (3) by bringing about a coupling reaction between a compound represented by formula (1) and a compound represented by formula (2), in the presence of a palladium compound, a ligand obtained by coordination in a palladium compound, a base, a C1-C40 carboxylic acid, and at least one kind of additive.</p>
申请公布号 MX2013001768(A) 申请公布日期 2013.03.22
申请号 MX20130001768 申请日期 2011.08.26
申请人 TEIJIN PHARMA LIMITED 发明人 MASATO KOMIYAMA
分类号 C07D277/20;A61K31/426;A61P19/06;A61P43/00;C07D277/56 主分类号 C07D277/20
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