PREPARATION OF DERIVATIVE OF 2-METHYL-4-AMINO-5-(SUBSTITUTED-1H-1,2,3-TRIAZOL)METHYL PYRIMIDINE AND MICROBICIDAL ACTIVITY THEREOF

摘要

Disclosed is a derivative of 2-methyl-4-amino-5-(substituted-1H-1,2,3-triazol)methyl pyrimidine of general formula I and microbicidal activity thereof. In the formula, R1 represents hydrogen, I; X represents O or NH; Y represents phenyl of substituted phenyl, benzoyl or substituted benzoyl, phenyloxyacetyl or substituted phenyloxyacetyl; the substituents on the phenyl rings which Y involves are: H, halogen, nitro, cyano, CF3, C1~4 alkyl, methoxyl, C1~2 carboxyl or carboxylic ester groups; any position of phenyl rings can be mono- or multi-substituted by identical or different substituents. The compound has a significant inhibition effect on cucumber bacterial angular leaf spot, tomato bacterial leaf spot, cucumber brown blot, cucumber downy mildew, rice sheath blight, Gibberella saubinetii, Altemaria solani, Botrytis cinerea, Alternaria alternata and Colletotrichum orbiculare and it can be used as an effective ingredient of microbicides.