STREPTAVIDIN MUTEIN EXHIBITING REVERSIBLE BINDING FOR BIOTIN AND STREPTAVIDIN BINDING PEPTIDE TAGGED PROTEINS

摘要

The present invention relates to a new streptavidin muteins. This mutein is binds both streptavidin binding peptide tagged and biotin or biotinylated molecules, and does so in a reversible fashion. As such, it is stable enough to allow reuse, and producible with reasonable production yield via secretion in a soluble functional state without the requirement of refolding via the tedious and expensive denaturation and renaturation processes.