The present invention relates to an injectable composition containing docetaxel. The injectable composition comprises: docetaxel or pharmaceutically acceptable salts thereof; HP-beta-CD; and a solvent, wherein 30 volume % or more of the entire solvent is ethanol and the injectable composition further comprises polyvinyl pyrrolidone for facilitating the dissolution of HP-beta-CD. The injectable transparent liquid composition according to the present invention not only has superior preservation stability but also has quite superior stability for perfusate dilution, such that the composition does not cause precipitation when diluted with a perfusate.
申请公布号
WO2012161520(A3)
申请公布日期
2013.03.21
申请号
WO2012KR04087
申请日期
2012.05.23
申请人
SK CHEMICALS CO., LTD.;SHIN, DONGCHUL;PARK, HYOJU;OH, JOON-GYO;LEE, BONG-YONG