摘要 |
<P>PROBLEM TO BE SOLVED: To surely provide one or more of desired throughput, sterility grade filtration, and robustness for membranes having isotropic (symmetric) and anisotropic (asymmetric) structures, e.g., multiple layer and composite membranes. <P>SOLUTION: A microfiltration membrane comprises (a) an asymmetric layer, (b) an isometric layer, and (c) an interface layer between the asymmetric layer and the isometric layer, the interface layer having a first portion contacting the asymmetric layer and a second portion contacting the isometric layer: wherein, (i) the asymmetric layer has a region contacting the first portion of the interface layer, the region including cells having a first porous structure; (ii) the isometric layer has a region contacting the second portion of the interface layer, the region including cells having a second porous structure; the first porous structure being larger than the second porous structure; and the first portion of the interface layer comprises cells having the first porous structure, and the second portion of the interface layer comprises cells having the second porous structure. Methods of making and using the membrane are also disclosed. <P>COPYRIGHT: (C)2013,JPO&INPIT |