发明名称 |
METHODS FOR REDUCING LIPOPROTEIN(a) LEVELS BY ADMINISTERING AN INHIBITOR OF PROPROTEIN CONVERTASE SUBTILISIN KEXIN-9 (PCSK9) |
摘要 |
The present invention provides methods for reducing lipoprotein(a) (Lp(a)) in patients. The methods of the present invention comprise selecting a patient who exhibits elevated serum Lp(a), and administering to the patient a pharmaceutical composition comprising a PCSK9 inhibitor. In certain embodiments, the PCSK9 inhibitor is an anti-PCSK9 antibody such as the exemplary antibody referred to herein as mAb316P. |
申请公布号 |
WO2013039969(A1) |
申请公布日期 |
2013.03.21 |
申请号 |
WO2012US54756 |
申请日期 |
2012.09.12 |
申请人 |
REGENERON PHARMACEUTICALS, INC.;SWERGOLD, GARY |
发明人 |
SWERGOLD, GARY |
分类号 |
C07K16/40;A61P3/06 |
主分类号 |
C07K16/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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