| 摘要 |
<p>(A) Compds. (I) R1=H, OH, (1-4C)alkyl, (1-4C) O alkyl, or (1-4C) O-alkanoyl. R2,R3 and R4=H, OH, (1-4C) O alkyl, or (1-4C) O-alkanoyl. with the proviso that if R1=H, R4 is not = H. (B) Acid addn. salts of I. (a) CNS and cardiovascular activity. (b) Enzyme inhibitors, e.g. of tyrosine hydroxylase. 8, 9 dihydroxy - 7-methylbenzo (b) quinolizine bromide (10g.), m.p. 305-310 deg., was hydrog. over PtO2(0.3g.) in H2O(500 ml.) and AcOH(250 ml.), filtered hot, evapd., and the residue recryst. from d.HBr, giving I-HBr, m.p.340 deg. (d).</p> |
