发明名称 |
PHARMACEUTICAL FORMULATION IN THE FORM OF BILAYERED TABLETS COMPRISING HMG-COA REDUCTASE INHIBITOR AND IRBESARTAN |
摘要 |
<p>Provided is a pharmaceutical formulation in the form of a bilayered tablet consisting of a first layer containing irbesartan or a pharmaceutically acceptable salt thereof and a second layer containing an HMG-CoA reductase inhibitor and a basic additive, which can improve the dissolution rate and stability of irbesartan and an HMG-CoA reductase inhibitor to enhance the bioavailability of the drug compared to conventional complex formulations and to minimize the generation of the related compounds, thereby being effectively used as a stable and superior therapeutic agent for hypertension and hypercholesterolemia.</p> |
申请公布号 |
EP2568972(A2) |
申请公布日期 |
2013.03.20 |
申请号 |
EP20110780838 |
申请日期 |
2011.05.13 |
申请人 |
HANMI SCIENCE CO., LTD. |
发明人 |
KIM, YONG IL;NA, YOUNG JUN;KIM, MIN JUNG;KIM, YOUNG-HUN;PARK, JAE HYUN;WOO, JONG SOO |
分类号 |
A61K9/24;A61K9/16;A61K9/20;A61K31/40;A61K31/415;A61K45/06;A61P3/00;A61P3/06 |
主分类号 |
A61K9/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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