摘要 |
1,229,723. Electro-chemical analysis. INTERNATIONAL BUSINESS MACHINES CORP. July 1, 1969 [July 15, 1968], No.33043/69. Heading G1N. The concentration of a component of a fluid 1 is measured using two identical glass electrodes 5, 6, the ion sensitive surface of one being contacted by an electrolyte 13 containing a reagent that reacts with said component and of the other being contacted by a similar electrolyte 14 not containing the reagent. Semipermeable membranes 3, 4 separate the electrolytes 13, 14 from the fluid 1 but allow the component to diffuse through. The electrodes may be pH sensitive and have HC1 electrolytes 7, 8 and Ag- AgCl leads 9, 10. Electrolytes 13, 14 may be KH 2 PO 4 solutions. For determining glucose in blood, the reagent is the enzyme glucose oxidase, producing gluconic acid and hydrogen peroxide. For determining urea in blood, the reagent is urease, producing ammonium carbonate. In an alternative arrangement Fig. 2 (not shown) the electrodes comprise ion sensitive glass tubes (20, 22) through which the fluid flows, membranes (23, 24) holding the electrolytes (32, -33) against the inner surfaces of the respective tubes. |