发明名称 USE OF METFORMIN IN COMBINATION WITH A GLUCOKINASE ACTIVATOR AND COMPOSITIONS COMPRISING METFORMIN AND A GLUCOKINASE ACTIVATOR.
摘要 The present invention provides uses of a glucokinase activator in combination with metformin. Uses include treating type 2 diabetes, lowering blood glucose, improving insulin sensitivity, enhancing phosphorylation of glucose, and improving the therapeutic effectiveness of metformin. The invention also provides pharmaceutical compositions that comprise a GK activator and metformin. The invention also provides a salt formed between metformin and a GK activator.
申请公布号 MX2012013617(A) 申请公布日期 2013.03.20
申请号 MX20120013617 申请日期 2011.05.24
申请人 TRANSTECH PHARMA, INC. 发明人 ADNAN M.M. MJALLI;MARIA CARMEN VALCARCE LOPEZ
分类号 C07D277/00 主分类号 C07D277/00
代理机构 代理人
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