发明名称 SOLID DISPERSANT COMPRISING TACROLIMUS AND A METHOD FOR PREPARING THE SAME
摘要 PURPOSE: A solid dispersant containing tacrolimus and a method for preparing the same are provided to simplify processes and to ensure eco-friendly and bio-affinity properties. CONSTITUTION: A method for preparing a solid dispersant containing tacrolimus comprises: a step of melting tacrolimus, a polymer melting base, a surfactant and forming a melting mixture; a step of cooling and solidifying the melting mixture; and a step of pulverizing the solidified mixture and preparing a solid dispersant. The polymer melting base is selected from the group consisting of polyethylene glycol, polypropylene glycol, polyvinylpyrrolidone, vinyl acetate copolymer, polyvinyl alcohol, and a polyacrylic acid polymer. [Reference numerals] (AA) Comparative embodiment 1; (BB) Comparative embodiment 2; (CC) Embodiment 4
申请公布号 KR20130028824(A) 申请公布日期 2013.03.20
申请号 KR20110092112 申请日期 2011.09.09
申请人 SAMYANG BIOPHARMACEUTICALS CORPORATION 发明人 KIM, KYUNG HEE;HWANG, SU JONG;HWANG, JUN SEOK;PAI, CHAUL MIN
分类号 C07D498/18;A61K31/436;A61P37/06;C07D498/14 主分类号 C07D498/18
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