发明名称 |
SOLID DISPERSANT COMPRISING TACROLIMUS AND A METHOD FOR PREPARING THE SAME |
摘要 |
PURPOSE: A solid dispersant containing tacrolimus and a method for preparing the same are provided to simplify processes and to ensure eco-friendly and bio-affinity properties. CONSTITUTION: A method for preparing a solid dispersant containing tacrolimus comprises: a step of melting tacrolimus, a polymer melting base, a surfactant and forming a melting mixture; a step of cooling and solidifying the melting mixture; and a step of pulverizing the solidified mixture and preparing a solid dispersant. The polymer melting base is selected from the group consisting of polyethylene glycol, polypropylene glycol, polyvinylpyrrolidone, vinyl acetate copolymer, polyvinyl alcohol, and a polyacrylic acid polymer. [Reference numerals] (AA) Comparative embodiment 1; (BB) Comparative embodiment 2; (CC) Embodiment 4
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申请公布号 |
KR20130028824(A) |
申请公布日期 |
2013.03.20 |
申请号 |
KR20110092112 |
申请日期 |
2011.09.09 |
申请人 |
SAMYANG BIOPHARMACEUTICALS CORPORATION |
发明人 |
KIM, KYUNG HEE;HWANG, SU JONG;HWANG, JUN SEOK;PAI, CHAUL MIN |
分类号 |
C07D498/18;A61K31/436;A61P37/06;C07D498/14 |
主分类号 |
C07D498/18 |
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