发明名称 |
Production of 2,3-butanediol in yeasts |
摘要 |
A high flux in conversion of pyruvate to acetolactate was achieved in yeast through expression of acetolactate synthase in the cytosol in conjunction with reduction in pyruvate decarboxylase activity. Additional manipulations to improve flux to acetolactate are reduced pyruvate dehydrogenase activity and reduced glycerol-3-phosphate dehydrogenase activity. Production of compounds having acetolactate as an upstream intermediate benefit from the increased conversion of pruvate to acetolactate in the described strains. |
申请公布号 |
GB2477385(B) |
申请公布日期 |
2013.03.20 |
申请号 |
GB20110000140 |
申请日期 |
2009.07.20 |
申请人 |
BUTAMAX (TM) ADVANCED BIOFUELS LLC |
发明人 |
LARRY CAMERON ANTHONY;LORI ANN MAGGIO-HALL |
分类号 |
C12N15/09;C12N15/81;C12P7/04;C12P7/16 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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