| 发明名称 |
NANOPARTICULATE FORMULATIONS COMPRISING HMG COA REDUCTASE INHIBITOR DERIVATIVES (STATINS),COMBINATIONS THEREOF AS WELL AS MANUFACTURING OF THESE PHARMACEUTICAL COMPOSITIONS |
| 摘要 |
<p num="1"><br/><br/><br/>The present invention is directed to nanoparticulate compositions comprising <br/>statin such as lovastatin or simvastatin including surface stabilizer. The <br/>statin particles of the composition have an effective average particle size of <br/>less than about 2000 nm. In another aspect of this invention, novel <br/>combinations of statins and other cholesterol lowering agents are described <br/>and methods of using same are taught.<br/>
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| 申请公布号 |
CA2488499(C) |
申请公布日期 |
2013.03.19 |
| 申请号 |
CA20032488499 |
申请日期 |
2003.06.10 |
| 申请人 |
ELAN PHARMA INTERNATIONAL, LTD. |
发明人 |
COOPER, EUGENE R.;HOVEY, DOUGLAS;CARY, GRETA;LINDNER, MARIE;LIVERSIDGE, ELAINE;LIVERSIDGE, GARY G.;RYDE, TUULA |
| 分类号 |
A61K9/06;A61K9/18;A61K9/10;A61K9/107;A61K9/14;A61K9/19;A61K9/20;A61K9/48;A61K9/72;A61K31/045;A61K31/185;A61K31/216;A61K31/22;A61K31/221;A61K31/34;A61K31/366;A61K31/381;A61K31/40;A61K31/4025;A61K31/405;A61K31/4155;A61K31/4164;A61K31/44;A61K31/455;A61K31/575;A61K31/661;A61K31/662;A61K31/717;A61K45/00;A61K45/06;A61K47/02;A61K47/04;A61K47/08;A61K47/10;A61K47/12;A61K47/14;A61K47/18;A61K47/20;A61K47/22;A61K47/24;A61K47/26;A61K47/28;A61K47/32;A61K47/34;A61K47/36;A61K47/38;A61K47/42;A61K47/44;A61P1/18;A61P3/00;A61P3/06;A61P9/00;A61P9/08;A61P9/10;A61P25/28;A61P41/00;A61P43/00 |
主分类号 |
A61K9/06 |
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