| 摘要 |
PURPOSE: A paste composition for ulcer treatment including honey and a manufacturing method thereof are provided to improve properties of cohesive property, transparency, sterilization, and storability. CONSTITUTION: A manufacturing method of paste composition for ulcer treatment comprises the following steps: manufacturing aqueous solution by dissolving biocompatible polymer in purified water(1 step); forming a gel state sheet by pouring aqueous solution into a tray(2 step); irradiating radiation in the aqueous solution(3 step); freeze-drying the gel(4 step); shattering the gel into pieces(5 step); and manufacturing paste by dissolving pulverized gel, honey, and preservative in the purified water(6 step). In step 1, weight ratio of biocompatible polymer mixed in the purified water is 1 to 30 weight%. In step 3, the radiation is gamma-ray, ultraviolet ray, or electronic beam. An amount of the radiant exposure is 2-200 kGy. In step 6, the weight ratio of the pulverized gel mixed as the paste is 1-10 weight%. In step 6, the weight ratio of honey which is mixed as paste is 5-30 weight%. |
