发明名称 |
1,4 oxazines as BACE1 and/or BACE2 inhibitors |
摘要 |
The present invention provides 1,4 Oxazines of formula I having BACE1 and/or BACE2 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease and type 2 diabetes. |
申请公布号 |
US8399459(B2) |
申请公布日期 |
2013.03.19 |
申请号 |
US201213357640 |
申请日期 |
2012.01.25 |
申请人 |
ANDREINI MATTEO;GABELLIERI EMANUELE;NARQUIZIAN ROBERT;TRAVAGLI MASSIMILIANO;WOSTL WOLFGANG;HOFFMANN-LA ROCHE INC.;SIENA BIOTECH SPA |
发明人 |
ANDREINI MATTEO;GABELLIERI EMANUELE;NARQUIZIAN ROBERT;TRAVAGLI MASSIMILIANO;WOSTL WOLFGANG |
分类号 |
A61K31/535;C07D265/28 |
主分类号 |
A61K31/535 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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