| 摘要 |
The invention concerns quinazoline derivatives of the Formula (I); wherein each of R<1>, R<2>, W, X<1>, X<2>, Z, a and b are as defined in the description; processes for their preparation; pharmaceutical compositions containing them and their use in the manufacture of a medicament for providing an anti-proliferative effect. The quinazoline derivatives of Formula (I) are expected to be useful in the treatment of diseases such as certain cancers mediated by erbB receptor tyrosine kinases, particularly EGFR tyrosine kinase. |
