The invention relates to a composition comprising ectoin, hydroxyectoin and/or a salt, ester or amide of these compounds for suppression of anti-apoptotic signals to neutrophilic granulocytes and other cells involved in inflammation. The retarded apoptosis of neutrophiles is a main component for various kinds of inflammation. Administration of ectoin achieves at least partial restoration of the normal apoptosis rate, which is associated with a corresponding improvement in the inflammation symptoms.
申请公布号
WO2013034299(A1)
申请公布日期
2013.03.14
申请号
WO2012EP03757
申请日期
2012.09.07
申请人
BITOP AG;UNFRIED, KLAUS;SYDLIK, ULRICH;KRUTMANN, JEAN;BILSTEIN, ANDREAS
发明人
UNFRIED, KLAUS;SYDLIK, ULRICH;KRUTMANN, JEAN;BILSTEIN, ANDREAS