CHIRAL COMPOUNDS OF VARYING CONFORMATIONAL RIGIDITY AND METHODS OF SYNTHESIS
摘要
Synthesis of compounds having varying degrees of conformational rigidity is obtained via a low cost, high yield and efficient synthetic reactions. The library of compounds is structurally diverse, having at least one or more chiral centers and providing large numbers of compounds having building block diversity and substantial scaffold diversity. The compounds further provide a novel method for obtaining candidate therapeutic agents for prevention, treatment or diagnosis of diseases.
申请公布号
WO2013036753(A1)
申请公布日期
2013.03.14
申请号
WO2012US54135
申请日期
2012.09.07
申请人
THE SCRIPPS RESEARCH INSTITUTE;MICALIZIO, GLENN, C.;KODADEK, THOMAS;SARKAR, MOHOSIN