| 发明名称 |
HALOGEN OR CYANO SUBSTITUTED THIENO [2,3-D]PYRIMIDINES HAVING MNK1/MNK2 INHIBITING ACTIVITY FOR PHARMACEUTICAL COMPOSITIONS |
| 摘要 |
The present invention relates to novel thienopyhmidine compounds of general formula (I), pharmaceutical compositions comprising these compounds and their therapeutic use for the prophylaxis and/or treatment of diseases which can be influenced by the inhibition of the kinase activity of Mnk1 and/or Mnk2 (Mnk2a or Mnk2b) and/or variants thereof. |
| 申请公布号 |
US2013065914(A1) |
申请公布日期 |
2013.03.14 |
| 申请号 |
US201113580184 |
申请日期 |
2011.02.25 |
| 申请人 |
HECKEL ARMIN;HIMMELSBACH FRANK;LEHMANN-LINTZ THORSTEN;REDEMANN NORBERT;SAUER ACHIM;THOMAS LEO;BLACK PHILLIP;BLACKABY WESLEY;DANILEWICZ JOHN;LINNEY IAN;AUSTEN MATTHIAS;SCHNEIDER MARTIN;SCHREITER KAY;BOEHRINGER INGELHEIM INTERNATIONAL GMBH |
发明人 |
HECKEL ARMIN;HIMMELSBACH FRANK;LEHMANN-LINTZ THORSTEN;REDEMANN NORBERT;SAUER ACHIM;THOMAS LEO;BLACK PHILLIP;BLACKABY WESLEY;DANILEWICZ JOHN;LINNEY IAN;AUSTEN MATTHIAS;SCHNEIDER MARTIN;SCHREITER KAY |
| 分类号 |
C07D495/04;A61K31/519;A61P3/00;A61P3/06;A61P3/10;A61P7/00;A61P13/12;A61P25/28;A61P29/00;A61P35/00 |
主分类号 |
C07D495/04 |
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