Implants for delivery of therapeutic agents such as opioids, and the manufacture and uses of such implants are provided. In particular, subcutaneous drug delivery systems having a biocompatible thermoplastic elastomeric polymer matrix, a therapeutic agent embedded homogeneously in said matrix, and a biocompatible drug impermeable cross-linked silicone polymer coating said matrix and methods of making the same are provided.
申请公布号
WO2013036775(A1)
申请公布日期
2013.03.14
申请号
WO2012US54176
申请日期
2012.09.07
申请人
AXXIA PHARMACEUTICALS, LLC;HOLL, RICHARD, J.;HARTMAN, KATHERINE;GROSSMAN, STUART, A.;POLLOCK, WAYNE, C.
发明人
HOLL, RICHARD, J.;HARTMAN, KATHERINE;GROSSMAN, STUART, A.;POLLOCK, WAYNE, C.