摘要 |
<P>PROBLEM TO BE SOLVED: To provide a means to simultaneously modulate expression of two or more genes in the same cell. <P>SOLUTION: Several gene expression cassettes for use in a multiple inducible gene expression system are constructed. The invention is useful in applications in which multiple gene regulation is critical. Thus, this invention overcomes a deficiency in the field of gene expression and is useful in the fields of functional genomics, proteomics, metabolomics, toxicology screening, cell-based high-throughput screening assays, protein production, gene therapies, and the like. The invention provides a means for parallel control of multiple genes in the same cell and enables to analyze complex biological phenomena, where multiple genes or pathways are involved, as well as to create new therapeutic applications. This invention relates to the field of biotechnology or genetic engineering. More specifically, the present invention relates to a multiple inducible gene regulation system that functions within cells to simultaneously control the quantitative expression of two or more genes. <P>COPYRIGHT: (C)2013,JPO&INPIT |