发明名称 IMAGING INFECTION WITH COMPOUND THAT BINDS TO THYMIDINE KINASE
摘要 <P>PROBLEM TO BE SOLVED: To provide an imaging agent for detecting bacterial infection in mammals. <P>SOLUTION: There is provided the imaging agent containing a labeled nucleoside analog for detecting bacterial infection in mammals. The nucleotide analog is preferably selected from the group consisting of: 2'-fluoro-2'-deoxy-1-&beta;-D-arabinofuranosyl-5-iodo-uracil (FIAU), 9-(4-fluoro-3-[hydroxymethyl]butyl)guanine (FHBG), 1-(2'-deoxy-2'-fluoro-&beta;-D-arabinofuranosyl)thymine (FMAU), and 2'-fluoro-2'-deoxy-1-&beta;-D-arabinofuranosyl-5-ethyl-uracil (FEAU). <P>COPYRIGHT: (C)2013,JPO&INPIT
申请公布号 JP2013049673(A) 申请公布日期 2013.03.14
申请号 JP20120204156 申请日期 2012.09.18
申请人 JOHNS HOPKINS UNIV 发明人 POMPER MARTIN G;BETTEGOWDA CHETAN;FOSS CATHERINE;ZHOU SHIBIN;KINZLER KENNETH;VOGELSTEIN BERT
分类号 A61K49/00;A61K51/00;G01T1/161 主分类号 A61K49/00
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