PROCESS FOR THE PREPARATION OF ESTETROL AND RELATED COMPOUNDS

摘要

The invention relates to a process for obtaining Estetrol and derivatives thereof of formula (I) or a salt or solvate thereof, wherein R represents H or anhydroxyl protecting group; the process comprising reacting a compound of formula (II) or a salt or solvate thereof, wherein R is as defined previously, with an oxidizing agent; the invention also relates to said 3-OH protected derivatives of formula (I) and intermediate products useful in the process.