发明名称 |
SYSTEMS AND METHODS FOR NETWORK-BASED BIOLOGICAL ACTIVITY ASSESSMENT |
摘要 |
<p>Systems and methods are disclosed herein for quantifying the response of a biological system to one or more perturbations based on measured activity data from a subset of the entities in the biological system. Based on the activity data and a network model of the biological system that describes the relationships between measured and non-measured entities, activities of entities that are not measured are inferred. The inferred activities are used for deriving a score quantifying the response of the biological system to a perturbation such as a response to a treatment condition. The score may be representative of the magnitude and topological distribution of the response of the network to the perturbation.</p> |
申请公布号 |
WO2013034300(A2) |
申请公布日期 |
2013.03.14 |
申请号 |
WO2012EP03760 |
申请日期 |
2012.09.07 |
申请人 |
PHILIP MORRIS PRODUCTS S.A;MARTIN, FLORIAN |
发明人 |
MARTIN, FLORIAN |
分类号 |
G06F19/00 |
主分类号 |
G06F19/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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