发明名称 Antagonistic selective binding agents of osteoprotegerin binding protein
摘要 Selective binding agents of osteoprotegerin binding protein (OPGbp) are provided by the invention. More particularly, the invention provides for antibodies and antigen binding domains which selectively bind to OPGbp and may be used to prevent or treat conditions relating to loss of bone mass. Nucleic acid molecules encoding said antibodies and antigen binding domains, and expression vectors and host cells for the production of same are also provided.
申请公布号 EP2105449(A3) 申请公布日期 2013.03.13
申请号 EP20080010991 申请日期 2001.02.23
申请人 AMGEN INC. 发明人 DESHPANDE, RAJENDRA V.;HITZ, ANNA;BOYLE, WILLIAM J.;SULLIVAN, JOHN K.
分类号 C07K16/28;C12N15/09;A61K38/22;A61K39/395;A61K45/00;A61P3/14;A61P19/00;A61P19/02;A61P19/10;A61P29/00;A61P35/00;A61P35/04;A61P43/00;C07K14/705;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/13;C12P21/08 主分类号 C07K16/28
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