摘要 |
<p>An N,N'-di(Py-aminoalkyl)-diazacycloalkane, or an N-oxide thereof, in which the alkylene radicals separate the attached N atoms by at least 2C, Py represents a pyrimidyl-2 residue which has in the 4 - position a free or substd. amino group and in the 6 - position an amino group, H, an aromatic or aliphatic hydrocarbon group opt. contg. O, N or S, or a free or etherified OH or SH group. Pref. cpds. have the formula:- A,A' = alkylene C2-C6 separating N atoms by is not 2C. R1R1'= NH2, substd. NH2. R3,R3'= H, NH2, alkyl, alkoxyalkyl R2,R2'= H, alkyl, alkoxyalkyl R4 = H, alkyl, n = 1-4. Antibacterial, antiprotozoal (inc.antimalarial) and anti-inflammatory agents. Animal feed supplements.</p> |