| 发明名称 |
2,5,6,7-TETRAHYDRO-[1,4]OXAZEPIN-3-YLAMINE OR 2,3,6,7-TETRAHYDRO-[1,4]OXAZEPIN-5-YLAMINE COMPOUNDS |
| 摘要 |
<p>This invention relates to compounds of the formula wherein A, B and R1 to R7 are as described below, or to pharmaceutically acceptable salts thereof. These compounds are BACE1 and/or BACE2 inhibitors and can be used as medicaments for the therapeutic and/or prophylactic treatment of diseases such as Alzheimer's disease, diabetes, particularly type 2 diabetes, and other metabolic disorders.</p> |
| 申请公布号 |
EP2566855(A1) |
申请公布日期 |
2013.03.13 |
| 申请号 |
EP20110720065 |
申请日期 |
2011.05.03 |
| 申请人 |
F.HOFFMANN-LA ROCHE AG;SIENA BIOTECH S.P.A. |
发明人 |
BANNER, DAVID;GUBA, WOLFGANG;HILPERT, HANS;HUMM, ROLAND;MAUSER, HARALD;MAYWEG, ALEXANDER, V.;NARQUIZIAN, ROBERT;POWER, EOIN;ROGERS-EVANS, MARK;ROMBACH, DIDIER;WOLTERING, THOMAS;WOSTL, WOLFGANG |
| 分类号 |
C07D267/10;A61K31/553;A61P25/28;C07D413/12;C07D417/12 |
主分类号 |
C07D267/10 |
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