发明名称 |
IMMUNOTHERAPY USING REDIRECTED ALLOGENEIC CELLS |
摘要 |
A method of treating a disease, such as cancer, by administering to a subject in need of such treatment an effective amount of allogeneic T cells with a MHC unrestricted chimeric receptor short time after partial lymphodepletion. The method also comprises administering one or more agents that delay egression of the allogeneic T cells from lymph nodes of said subject during adoptive transfer of said allogeneic T cells to the subject by trapping the T cells in the lymph nodes. |
申请公布号 |
EP2566954(A1) |
申请公布日期 |
2013.03.13 |
申请号 |
EP20110778231 |
申请日期 |
2011.05.04 |
申请人 |
YEDA RESEARCH AND DEVELOPMENT CO. LTD. |
发明人 |
ESHHAR, ZELIG;MARCUS, ASSAF;WAKS, TOVA |
分类号 |
C12N5/02;C12N15/11 |
主分类号 |
C12N5/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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