发明名称 DESAZADESFERROTHIOCIN AND DESAZADESFERROTHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS
摘要 <p>Disclosed herein are new compounds of desazadesferrothiocin polyether (DADFT-PE) analogues, as well as pharmaceutical compositions comprising them and their application as metal chelation agents for the treatment of disease. Methods of chelation of iron and other metals in a human or animal subject are also provided for the treatment of metal overload and toxicity.</p>
申请公布号 EP2566854(A2) 申请公布日期 2013.03.13
申请号 EP20110778269 申请日期 2011.05.04
申请人 SHIRE LLC 发明人 MALECHA, JAMES, W.
分类号 C07D231/14;A61K31/4164;A61K31/421;A61P3/10;A61P31/12;C07D233/28;C07D263/16;C07D277/12;C07D277/56 主分类号 C07D231/14
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