| 摘要 |
The present invention provides a cationic lipid, which allow nucleic acids to be easily introduced into cells, represented by formula (I)
(wherein: R 1 and R 2 are, the same or different, alkenyl, etc, and
X 1 and X 2 are hydrogen atoms, or are combined together to form a single bond or alkylene, and
X 3 is absent or is alkyl, etc,
Y is absent or anion,
a and b are, the same or different, 0 to 3, and
L 3 is a single bond, etc,
R 3 is alkyl, etc,
L 1 and L 2 are -0-, -CO-O- or -O-CO-),
a composition comprising the cationic lipid and a nucleic acid, and a method for introducing a nucleic acid into a cell by using the composition comprising the cationic lipid and the nucleic acid, and the like. |
