发明名称 |
THE USE OF INHIBITORS OF BRUTON'S TYROSINE KINASE (BTK). |
摘要 |
Disclosed herein are methods for treating a cancer comprising: a. administering a Btk inhibitor to a subject sufficient to result in an increase or appearance in the blood of a subpopulation of lymphocytes defined by immunophenotyping; b. determining the expression profile of one or more biomarkers from one or more subpopulation of lymphocytes; and c. administering a second agent based on the determined expression profile. |
申请公布号 |
MX2012014049(A) |
申请公布日期 |
2013.03.12 |
申请号 |
MX20120014049 |
申请日期 |
2011.06.03 |
申请人 |
PHARMACYCLICS, INC. |
发明人 |
JOSEPH J. BUGGY;LAURENCE ELIAS;DAVID J. LOURY;TARAK D. MODY;GWEN FYFE;ERIC HEDRICK |
分类号 |
A61K31/519;A61K31/505;A61P35/00;A61P35/02 |
主分类号 |
A61K31/519 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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