TABLET QUICKLY DISINTEGRATING CONTAING MEGESTROL AND METHOD FOR PRODUCING THE SAME

摘要

PURPOSE: A megestrol rapidly disintegrating a tablet and a method for manufacturing the same are provided to ensure quick disintegration and administration convenience and to enhance drug release and absorption. CONSTITUTION: A megestrol rapidly disintegrating a tablet contains megestrol acetate as an active ingredient. The tablet is selected from a group consisting of a rapid disintegrant, a disintegrant, a binder, a flavoring agent, a sweetener, a lubricant, a polymer carrier, and an absorption enhancer. The rapid disintegrant is D-mannitol, sorbitol, fructose, lactose, dextrose, xylitol, white sugar, glucose, maltodextrin, levulose, erythritol, cellulose, fine crystalline cellulose, starch and a derivative thereof, -MELT (Fuji chemical), Ludiflash, spray-dried mannitol(Merck), Starlac(Roquette), and dextrate(Edward Mendell). [Reference numerals] (AA) 0 second; (BB) 10 seconds; (CC) 20 seconds; (DD) 30 seconds; (EE) 40 seconds