发明名称 Protein markers for the detection of thyroid cancer metastasis
摘要 This invention relates, e.g., to a method for detecting the presence of lymph node metastases in a subject having papillary thyroid carcinoma (PTC), comprising measuring in a sample from the subject the amount of expression (e.g., the amount of protein, or the amount of mRNA encoding the protein) of one or more of the following proteins: (a) LIMD2, and/or (b) PTPRC, and/or (c) LTB, and/or (d) CD48, and/or (e) ABCC3, wherein a significant amount of over-expression of one or more of protein(s) (a)-(e), compared to the baseline value, indicates that lymph node metastases are likely to be present in the subject.
申请公布号 US8394580(B2) 申请公布日期 2013.03.12
申请号 US20080222876 申请日期 2008.08.18
申请人 RIGGINS GREGORY;CERUTTI JANETE;THE JOHNS HOPKINS UNIVERSITY 发明人 RIGGINS GREGORY;CERUTTI JANETE
分类号 C12Q1/00;C12Q1/68;G01N1/00;G01N33/48;G01N33/53;G01N33/567;G01N33/574 主分类号 C12Q1/00
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